New biologically active marine sesquiterpenoid and steroid from the okinawan sponge of the genus Axinyssa.

نویسندگان

  • Makoto Iwashima
  • Ikuo Terada
  • Kazuo Iguchi
  • Takao Yamori
چکیده

A new bisabolane-type sesquiterpenoid, (E)-3-isocyanobisabolane-7,10-diene (1), and a new epidioxyergostane-type steroid, 9(11)-dehydroaxinysterol (2), were isolated from the Okinawan sponge of the genus Axinyssa. Their structures were elucidated based on the results of spectroscopic analysis and chemical conversion. Epidioxysterol 2 was found to show significant growth inhibitory effects against human cancer cell lines.

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عنوان ژورنال:
  • Chemical & pharmaceutical bulletin

دوره 50 9  شماره 

صفحات  -

تاریخ انتشار 2002